PK/PD modeling and simulation is a rapidly evolving science and emerged to be the focus of considerable attention since it is vital for linking PK information to measures of drug effect and clinical outcome. The implementation of PK/PD modeling and simulation approaches has an enormous impact on designing safer and more efficient trials within all stages of drug development. It is also particularly useful to support either a full or partial extrapolation of data from available adult populations to guide the design of pediatric studies, providing insight and guidance on the rational selection of pediatric doses and dose regimens.
Our PK/PD modeling and simulation services include:
- Non-compartmental analysis (NCA)
- Compartmental analysis
- Direct/Indirect PD response models
- Exposure-response models
- Population PK/PD analysis
- Optimal sampling design